Membraneless Compartmentalization Facilitates Enzymatic Cascade Reactions and Reduces Substrate Inhibition
نویسندگان
چکیده
منابع مشابه
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The Michaelis-Menten equation provides a hundred-year-old prediction by which any increase in the rate of substrate unbinding will decrease the rate of enzymatic turnover. Surprisingly, this prediction was never tested experimentally nor was it scrutinized using modern theoretical tools. Here we show that unbinding may also speed up enzymatic turnover--turning a spotlight to the fact that its a...
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ژورنال
عنوان ژورنال: ACS Applied Materials & Interfaces
سال: 2018
ISSN: 1944-8244,1944-8252
DOI: 10.1021/acsami.8b07573